分析化学家

1959年毕业于苏联列宁格勒大学化学系。

1959-62年在科学院化学所工作。

1962年至今在湖南大学任教。

1981年任教授，1983年任博士导师。

1991年当选中科院学部委员(院士)。

1993-99年任湖南大学校长。

任《化学传感器》主编。曾任《高等学校化学学报》副主编及英国皇家化学会期刊“Analyst”地区顾问编委。现任国际化学计量学学会期刊《Journal of Chemometrics》编辑及国际分析化学期刊《Analytica Chimica Acta》顾问编委。

研制成功多种新型电化学及光化学传感器，并实现产业化生产。合成多种新的分析及增敏试剂与离子载体，建立铌等稀有金属分析方法。创立多种新型稳健化学计量学多元校正及化学模式识别分类方法，倡导作为化学量测基础理论与方法学的独特的化学计量学教学体系。

[1] Jinwen Liu, Ying Luo, Yumin Wang, Luying Duan, Jianhui Jiang and Ruqin Yu. Graphitic Carbon Nitride Nanosheets-based Ratiometric Fluorescent Probe for Highly Sensitive Detection of H2O2 and Glucose. ACS Applied Materials & Interfaces, 2016, 8: 33439-33445.

[2] Wenfang Du, Mengmei Lv, Junjie Li, Ruqin Yu and Jianhui Jiang. A ligation-based loop-mediated isothermal amplification (ligation-LAMP) strategy for highly selective microRNA detection. Chemical Communications, 2016, 52(86): 12721-12724.

[3] Liping Qiu, Zhifa Shen, Zaisheng Wu, Guoli Shen and Ruqin Yu. Discovery of the unique self-assembly behavior of terminal suckers-contained dsDNA onto GNP and novel “light-up” colorimetric assay of nucleic acids. Biosensors and Bioelectronics, 2015, 64: 292-299.

[4] Xidong Duan, Chen Wang, Zheng Fan, Guolin Hao, Liangzhi Kou, Udayabagya Halim, Honglai Li, Xueping Wu, Yicheng Wang and Jianhui Jiang. Synthesis of WS2 x Se2–2 x Alloy Nanosheets with Composition-Tunable Electronic Properties. Nano Letters, 2015, 16(1): 264-269.

[5] Qiang Xi, Dianming Zhou, Yingya Kan, Jia Ge, Zhenkun Wu, Ruqin Yu and Jianhui Jiang. Highly sensitive and selective strategy for microRNA detection based on WS2 nanosheet mediated fluorescence quenching and duplex-specific nuclease signal amplification. Analytical Chemistry, 2014, 86(3): 1361-1365.

[6] Hongbo Li, Zaisheng Wu, Zhifa Shen, Guoli Shen and Ruqin Yu. Architecture based on the integration of intermolecular G-quadruplex structure with sticky-end pairing and colorimetric detection of DNA hybridization. Nanoscale, 2014, 6(4): 2218-2227.

[7] Jia Ge, Lijuan Tang, Qiang Xi, Xiping Li, Ruqin Yu, Jianhui Jiang and Xia Chu. A WS 2 nanosheet based sensing platform for highly sensitive detection of T4 polynucleotide kinase and its inhibitors. Nanoscale, 2014, 6(12): 6866-6872.

[8] Liangliang Zhang, Jingjin Zhao, Min Duan, Hua Zhang, Jianhui Jiang and Ruqin Yu. Inhibition of dsDNA-templated copper nanoparticles by pyrophosphate as a label-free fluorescent strategy for alkaline phosphatase assay. Analytical Chemistry, 2013, 85(8): 3797-3801.

[9] Cui Wang, Hui Zhou, Wenping Zhu, Hongbo Li, Jianhui Jiang, Guoli Shen and Ruqin Yu. Ultrasensitive electrochemical DNA detection based on dual amplification of circular strand-displacement polymerase reaction and hybridization chain reaction. Biosensors and Bioelectronics, 2013, 47: 324-328.

[10] Hongbo Li, Zaisheng Wu, Liping Qiu, Jinwen Liu, Cui Wang, Guoli Shen and Ruqin Yu. Ultrasensitive label-free amplified colorimetric detection of p53 based on G-quadruplex MBzymes. Biosensors and Bioelectronics, 2013, 50: 180-185.

[11] Jingjin Zhao, Liangliang Zhang, Jianhui Jiang, Guoli Shen and Ruqin Yu. A label-free fluorescence DNA probe based on ligation reaction with quadruplex formation for highly sensitive and selective detection of nicotinamide adenine dinucleotide. Chemical Communications, 2012, 48(37): 4468-4470.

[12] Jingjin Zhao, Chunfei Chen, Liangliang Zhang, Jianhui Jiang and Ruqin Yu. An electrochemical aptasensor based on hybridization chain reaction with enzyme-signal amplification for interferon-gamma detection. Biosensors and Bioelectronics, 2012, 36(1): 129-134.

[13] Liangliang Zhang, Jingjin Zhao, Jianhui Jiang and Ruqin Yu. Enzyme-regulated unmodified gold nanoparticle aggregation: a label free colorimetric assay for rapid and sensitive detection of adenosine deaminase activity and inhibition. Chemical Communications, 2012, 48(89): 10996-10998.

[14] Liangliang Zhang, Jingjin Zhao, Jianhui Jiang and Ruqin Yu. A target-activated autocatalytic DNAzyme amplification strategy for the assay of base excision repair enzyme activity. Chemical Communications, 2012, 48(70): 8820-8822.

[15] Huiwang Wu, Shucheng Liu, Jianhui Jiang, Guoli Shen and Ruqin Yu. A sensitive electrochemical biosensor for detection of DNA methyltransferase activity by combining DNA methylation-sensitive cleavage and terminal transferase-mediated extension. Chemical Communications, 2012, 48(50): 6280-6282.

先后获国家自然科学二等、三等奖、省科技进步一等奖、光召科技奖与科学技术杰出贡献奖。