1993年本科毕业于湖南大学化学系，分别于1996年和1999年获得湖南大学化学化工学院硕士和博士学位。

1999年至2005年于湖南师范大学化学化工学院工作。

2006年调入湖南大学化学生物传感与计量学国家重点实验室工作，任教授，2007年遴选为博士生导师。

先后主持了国家自然科学基金面上项目4项，作为课题组长与企业联合承担了国家863计划重点项目1项，作为湖南大学课题组负责人参与了南方医科大学为主承担的国家自然科学基金-广东省联合基金重点项目。研究成果获教育部自然科学一等奖(排名第五)。SCI收录相关学术论文34篇，引用558次。以通讯作者身份在Angewandte Chemie International Edition(1篇)、 Analytical Chemistry(4篇)、Biosensors and Bioelectronics(4篇)等国际分析化学重要SCI期刊上发表论文25篇(影响因子IF> 5的论文9篇)，引用426次，单篇最高引用92次，并得到了国内外同行的较高评价。

1. Haibo Wang, Qing Zhang, Xia Chu*, Tingting Chen, Jia Ge, Ruqin Yu, Graphene Oxide-Peptide Conjugate as Intracellular Protease Sensor for Caspase-3 Activation Imaging in Live Cells. Angewandte Chemie International Edition 2011, 50, 7065– 7069.

2. Li-Juan Ou, Pei-Yan Jin, Xia Chu,* Jian-Hui Jiang, and Ru-Qin Yu, Sensitive and Visual Detection of Sequence-Specific DNA-Binding Protein via a Gold Nanoparticle-Based Colorimetric Biosensor. Anal. Chem. 2010, 82, 6015– 6024.

3. Jishan Li, Ting Deng, Xia Chu,* Ronghua Yang,* Jianhui Jiang, Guoli Shen, and Ruqin Yu, Rolling Circle Amplification Combined with Gold Nanoparticle Aggregates for Highly Sensitive Identification of Single-Nucleotide Polymorphisms. Anal. Chem. 2010, 82, 2811– 2816.

4. Li-Juan Ou, Si-Jia Liu, Xia Chu,* Guo-Li Shen, and Ru-Qin Yu, DNA Encapsulating Liposome Based Rolling Circle Amplification Immunoassay as a Versatile Platform for Ultrasensitive Detection of Protein. Anal. Chem. 2009, 81, 9664– 9673.

5.Long Zhou, Li-Juan Ou, Xia Chu,* Guo-Li Shen, and Ru-Qin Yu, Aptamer-Based Rolling Circle Amplification: A Platform for Electrochemical Detection of Protein. Anal. Chem. 2007, 79, 7492-7500.

6. Haibo Wang, Tingting Chen, Shuang Wu, Xia Chu*, Ruqin Yu，A Novel Biosensing Strategy for Screening G-quadruplex Ligands Based on Graphene Oxide Sheets. Biosensors and Bioelectronics 2012, doi:10.1016/j.bios.2012.01.023.

7. Danhong Wu, Qing Zhang, Xia Chu,* Haibo Wang, Guoli Shen, Ruqin Yu, Ultrasensitive Electrochemical Sensor for Mercury (II) Based on Target-Induced Structure-Switching DNA. Biosensors and Bioelectronics 2010, 25, 1025– 1031.

8. Peng Zhang, Xia Chu*, Xiangmin Xu, Guoli Shen, Ruqin Yu, Electrochemical Detection of Point Mutation Based on Surface Ligation Reaction and Biometallization. Biosensors and Bioelectronics 2008, 23, 1435– 1441.

9. Bo Qu, Lei Guo, Xia Chu*, Dan-Hong Wu, Guo-Li Shen, Ru-Qin Yu, An Electrochemical Immunosensor Based on Enzyme-Encapsulated Liposomes and Biocatalytic Metal Deposition. Analytica Chimica Acta 2010, 663, 147– 152.

10. Yun Tan, Xia Chu*, Guo-Li Shen, Ru-Qin Yu, A Signal-Amplified Electrochemical Immunosensor for Aflatoxin B1 Determination in Rice. Analytical Biochemistry, 2009, 387, 82– 86.

1篇论文入选为“ 中国百篇最具影响优秀国际学术论文” 。